Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones(H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

 

產(chǎn)品性質(zhì)

別名	EC 3.5.1.98; HA6116; HD 4; HD4; HDAC 4; HDAC A; HDAC4; HDAC4_HUMAN; HDACA; Histone Deacetylase 4; Histone Deacetylase A; KIAA0288
SwissProt ID	P56524
基因ID	9759
免疫原	Purified recombinant human HDAC4 protein fragments expressed in E.coli.
緩沖液	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
分子量	Calculated MW: 119 kDa; Observed MW: 140 kDa
克隆類型	Monoclonal Antibody
宿主	Mouse
物種反應(yīng)	Human, Mouse, Rat, Monkey
推薦應(yīng)用	WB, IP
純化方式	Affinity Purified

 

應(yīng)用

稀釋比 WB:1/500-1/1000; IP:1/20;

 

儲(chǔ)存條件

-25~-15℃保存

 

注意事項(xiàng)

1. 避免反復(fù)凍融。

2. 本產(chǎn)品僅作科研用途。

3. 為了您的安全和健康，請(qǐng)穿實(shí)驗(yàn)服并佩戴一次性手套操作。

 

產(chǎn)品數(shù)據(jù)

Western blot

Immunoprecipitation

 

Ver.CN20230921