Biotinylated Human IL-1R3/IL-1 RAcP Protein, His-Avi Tag
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產(chǎn)品說明書
FAQ
COA
已發(fā)表文獻(xiàn)
IL-1R3, also known as IL-1 Receptor Accessory Protein (IL-1 RAcP), is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the receptors for IL-1 alpha, IL-1 beta, IL-33, and IL-36. Within the ECD, human IL-1 RAcP shares 86% aa sequence identity with mouse and rat IL-1 RAcP. It is a subunit of the functional signaling complex with IL-1 RI and associates with IL-1 RII in a non-signaling receptor complex. In addition, it interacts with ST2/IL-1 R4 on mast cells and Th2 cells to create a functional IL-33 receptor complex.
產(chǎn)品性質(zhì)
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Synonyms |
IL1RAP; IL-1RAP; C3orf13; IL-1 R3; IL-1 RAcP |
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Uniprot No. |
Q9NPH3-1 |
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Source |
Recombinant Biotinylated Human IL-1R3/IL-1 RAcP Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Ser21-Glu359. |
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Molecular Weight |
The protein has a predicted MW of 42 kDa. Due to glycosylation, the protein migrates to 52-70 kDa based on Tris-Bis PAGE result. |
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Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
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Purity |
> 95% as determined by SDS-PAGE and HPLC |
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Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
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Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. |
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Reconstitution |
Centrifuge tubes before opening. Reconstituting to a concentration more than 100μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
運(yùn)輸與保存方法
The products are shipped with ice pack and can be stored at -20℃ for 1 year.
2-7 days, 2 to 8 °C under sterile conditions after reconstitution.
3 -6 months, -20 to -80°C under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
注意事項(xiàng)
- For your safety and health, please wear lab coats and disposable gloves for operation.
- For research use only!
產(chǎn)品數(shù)據(jù)
HB230207
