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          Recombinant FITC-Labeled Human EGFRVIII Protein, His-Avi Tag
           
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          產(chǎn)品說明書
                  
          FAQ
                  
          COA
                  
          已發(fā)表文獻(xiàn)
                  
           
          

           
          


          The epidermal growth factor receptor (EGFR) subfamily of receptor tyrosine kinases comprises four members: EGFR (HER1), ErbB2, ErbB3, and ErbB4. EGFRvIII is tumor specific, and has not been found in normal tissues. EGFRvIII is highly tumorigenic, and can cause aggressive tumor phenotype, with increased invasion, proliferation, angiogenesis, and evasion of apoptosis.
          


           
          


          產(chǎn)品性質(zhì)
          


          
	
		
          
			
			
          Synonyms
          
			          		
			
			
          ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2
          
			          		
		
          
		
          
			
			
          Accession
          
			          		
			
			
          NP_001333870.1
          
			          		
		
          
		
          
			
			
          Source
          
			          		
			
			
          Recombinant FITC-Labeled Human EGFRVIII Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Leu25-Ser378.
          
			          		
		
          
		
          
			
			
          Molecular Weight
          
			          		
			
			
          The protein has a predicted MW of 41.6 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.
          
			          		
		
          
		
          
			
			
          Purity
          
			          		
			
			
          > 95% as determined by SDS-PAGE.
          
			          		
		
          
		
          
			
			
          Endotoxin
          
			          		
			
			
          < 1.0 EU per 1μg of the protein by the LAL method.
          
			          		
		
          
		
          
			
			
          Formulation
          
			          		
			
			
          Supplied as from 0.22μm filtered solution in PBS (pH 7.4). 
          
			          		
		
          
	          

          


           
          


          運輸與保存方法
          


          The products are shipped with ice pack and can be stored at -80℃ for 1 year.
          


          Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
          


           
          


          注意事項
          


          1.For your safety and health, please wear lab coats and disposable gloves for operation.
          


          2.For research use only!
          


           
          

          


          產(chǎn)品數(shù)據(jù)
          


          SDS-PAGE
          


          


          FACS Data
          


          


          HB230120
          

             
           
           
           
           
           
           
           
          400-6111-883