问鼎娱乐.com|极速飞艇的冠亚和计划|极速赛车计划群群名|sg幸运飞艇计划官方版下载

<label id="6kt4j"></label>

    <li id="6kt4j"></li>
    1. 

          2. 
    
            
           
           
           
           
          Recombinant Rat IFN-gamma Protein
           
          更多活動更多優(yōu)惠，盡在翌圣商城》
           
           
           
          批量采購， 請點擊詢價
           
           
          產(chǎn)品說明書
                  
          FAQ
                  
          COA
                  
          已發(fā)表文獻
                  
           
          

          Interferon-gamma (IFN-γ), also known as Type II interferon or immune interferon, is a pleiotropic cytokine which is now recognised as an important modulator of the immune response. Mature human IFN-γ exists as a non-covalently linked homodimer of 20-25 kDa variably glycosylated subunits. It shares 90% amino acid (aa) sequence identity with rhesus IFN-γ, 59%64% with bovine, canine, equine, feline, and porcine IFN-γ, and 37%43% with cotton rat, mouse, and rat IFN-γ. Interferons have had increasing clinical usage in the treatment of a variety of disorders, at times being used in combination with chemo‐ or radiotherapy. IFN-γ increases the potential immunogenicity of vascular endothelial cells by up-regulation of intercellular adhesion molecule-1 (ICAM-1) and class I MHC antigen expression and by induction of class II MHC antigens and certain chemokines.
          


           
          


          Product Properties
          


          
	
		
          
			
			
          Synonyms
          
			          		
			
			
          Interferon-gamma, IFN-γ, IFG, IFI, IFNG, IFNgamma, IFN-gamma.
          
			          		
		
          
		
          
			
			
          Accession
          
			          		
			
			
          P01581
          
			          		
		
          
		
          
			
			
          GeneID
          
			          		
			
			
          25712
          
			          		
		
          
		
          
			
			
          Source
          
			          		
			
			
          E.coli-derived rat IFN-γ protein, Gln23-Cys156.
          
			          		
		
          
		
          
			
			
          Molecular Weight
          
			          		
			
			
          Approximately 15.5 kDa.
          
			          		
		
          
		
          
			
			
          AA Sequence
          
			          		
			
			
          QGTLIESLES LKNYFNSSSM DAMEGKSLLL DIWRNWQKDG NTKILESQII SFYLRLFEVL KDNQAISNNI SVIESHLITN FFSNSKAKKD AFMSIAKFEV NNPQIQHKAV NELIRVIHQL SPESSLRKRK RSRC
          
			          		
		
          
		
          
			
			
          Tag
          
			          		
			
			
          None
          
			          		
		
          
		
          
			
			
          Physical Appearance
          
			          		
			
			
          Sterile Filtered White lyophilized (freeze-dried) powder.
          
			          		
		
          
		
          
			
			
          Purity
          
			          		
			
			
          > 97% by SDS-PAGE and HPLC analyses.
          
			          		
		
          
		
          
			
			
          Biological Activity
          
			          		
			
			
          The ED50 as determined by an anti-viral assay using murine L929 cells infected with encephalomyocarditis (EMC) virus is less than 0.1 ng/mL, corresponding to a specific activity of > 1.0 × 107 IU/mg. Fully biologically active when compared to standard. 
          
			          		
		
          
		
          
			
			
          Endotoxin
          
			          		
			
			
          < 0.1 EU per 1μg of the protein by the LAL method.
          
			          		
		
          
		
          
			
			
          Formulation
          
			          		
			
			
          Lyophilized from a 0.2 μm filtered concentrated solution in 1 × PBS, pH 7.4, 1 mM DTT, 5% Trehalose and 0.05% Tween-80. 
          
			          		
		
          
		
          
			
			
          Reconstitution
          
			          		
			
			
          We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10 mM HAc to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.
          
			          		
		
          
	          

          


           
          

          


          Shipping and Storage
          


          The products are shipped with ice pack and can be stored at -20 ℃ for 1 year.
          


          1 month, 2 to 8 °C under sterile conditions after reconstitution.
          


          3 months, -20 °C under sterile conditions after reconstitution.
          


          Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
          


           
          


          Cautions
          


            
	
          1. Avoid repeated freeze-thaw cycles.
            2. 
	
          2. For your safety and health, please wear lab coats and disposable gloves for operation.
            3. 
	
          3. For research use only!
            4. 

          


          HB221025
          

             
           
           
           
           
           
           
           
          400-6111-883