產(chǎn)品簡介

 

MMAE, or monomethyl auristatin E, is a potent cytotoxic agent commonly used in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. It is an antimitotic agent which inhibits cell division by blocking the polymerization of tubulin.

 

產(chǎn)品性質(zhì)

 

來源	Monoclonal anti-MMAE antibody, is produced from a hybridoma which was obtained from a mouse immunized with MMAE.
緩沖液	1×PBS, pH7.4.
克隆類型	Monoclonal Antibody
亞型	IgG1
宿主	Mouse
消光系數(shù)	1.4
濃度	1 mg/mL
純度	＞94% as determined by reduced SDS-PAGE ＞97% as determined by non-reduced SDS-PAGE > 98% as determined by SEC-HPLC
活性	EC50=6.3 ng/mL by ELISA
應(yīng)用	ELISA

 

儲(chǔ)存條件

 

-25~-15℃保存

 

注意事項(xiàng)

 

1. 避免反復(fù)凍融。

2. 本產(chǎn)品僅作科研用途。

3. 為了您的安全和健康，請(qǐng)穿實(shí)驗(yàn)服并佩戴一次性手套操作。

 

產(chǎn)品數(shù)據(jù)  

 

SDS-PAGE

 

SEC-HPLC

ELISA Data
 

Ver.CN20240726