產(chǎn)品說明書
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產(chǎn)品簡介
Thrombopoietin (Tpo), is a key regulator of megakaryocytopoiesis and thrombopoiesis.TPO is a lineage-specific growth factor produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor, and acts as an important regulator of circulating platelets.
性能參數(shù)
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Synonyms |
Thrombopoietin, Megakaryocyte colony-stimulating factor, c-MPL Ligand, MGDF |
|
Uniprot No. |
P40226 |
|
Source |
Mouse TPO Protein is expressed from HEK293 without tag. It contains Ser22-Thr356. |
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Molecular Weight |
The protein has a predicted 35.6 kDa |
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Purity |
> 95% as determined by SDS-PAGE. |
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Biological Activity |
Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The EC50 for this effect is 0.04-2.4 ng/mL. |
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Endotoxin |
< 0.01 EU per 1μg of the protein by the LAL method. |
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Formulation |
Dissolved in sterile PBS buffer. This solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening. |
儲存條件
The product should be stored at -85~-65℃ for 1 year from date of receipt.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
注意事項
- Please operate with lab coats and disposable gloves,for your safety.
- This product is for research use only.
Ver. CN20240202
